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GLP-1 & Weight Loss Providers Compared

Semaglutide, tirzepatide, and compounded GLP-1 treatments from 13 licensed US telehealth providers. We compare them so you don't have to.

13 Providers Compared
All Licensed & US-Based
Updated April 2026

GLP-1 · Weight Loss

Compare GLP-1 providers

Every provider listed uses US-licensed physicians and ships prescriptions to your door. Click through to check eligibility and current pricing.

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How GLP-1 medications work

Understanding the science behind semaglutide, tirzepatide, and other GLP-1 treatments.

Mimics a natural hormone

GLP-1 (glucagon-like peptide-1) is a hormone your body naturally produces after eating. These medications mimic that hormone at higher, sustained levels, helping regulate appetite and blood sugar.

Slows gastric emptying

These medications slow down how fast food leaves your stomach, helping you feel full longer. This naturally reduces calorie intake without the constant willpower battle of traditional dieting.

Prescription required

GLP-1 medications require a prescription from a licensed provider. The telehealth platforms listed above connect you with licensed prescribers who evaluate your health history and determine if treatment is appropriate.

Possible side effects

Common side effects include nausea, diarrhea, and constipation — especially when starting or increasing dosage. Most are temporary and manageable. Your provider will help adjust dosing as needed.

Important: GLP-1 medications are generally prescribed for adults with a BMI of 30+ (or 27+ with weight-related health conditions). A licensed provider will evaluate whether you're a candidate during your consultation.

Branded vs. compounded GLP-1

One of the biggest decisions you'll make is whether to go with brand-name or compounded GLP-1 medications.

Brand-Name (Wegovy, Zepbound, Mounjaro)

FDA-approved and manufactured by Novo Nordisk and Eli Lilly. Extensive clinical trial data. Gold standard, premium price.

Typical cost: $800–$1,600+/month without insurance

Best for: Patients who want the exact FDA-approved formulation and can afford the cost or have insurance coverage.

Compounded Semaglutide / Tirzepatide

Made by licensed compounding pharmacies using the same active ingredient. Legal alternatives offered by most telehealth providers at a fraction of the cost.

Typical cost: $150–$500/month depending on provider

Best for: Patients who want GLP-1 treatment without insurance coverage or at a more accessible price point.

Note: The FDA's position on compounded GLP-1 medications has evolved. Compounding is permitted when there is a documented shortage of the brand-name drug, or under other specific conditions. Always verify with your provider that your medication comes from a licensed, inspected compounding pharmacy.

Common questions

FAQ

Do I need insurance to use these providers?

No. Most providers listed are cash-pay / subscription-based and bypass insurance entirely. This is often faster and cheaper than the insurance route for GLP-1s. HSA and FSA cards are typically accepted. Sesame Care is the exception — it's built to work with insurance for brand-name Wegovy and Zepbound.

How quickly can I start treatment?

Most providers review your consultation within 24–48 hours. If approved, medication typically ships within a few business days. Total time from sign-up to receiving your medication is usually 3–7 days.

What's the difference between semaglutide and tirzepatide?

Both are injectable GLP-1 medications used for weight loss. Semaglutide (Ozempic, Wegovy) targets one receptor (GLP-1). Tirzepatide (Mounjaro, Zepbound) targets two receptors (GLP-1 and GIP), which may produce greater weight loss in some patients. Your provider will recommend which is better for your situation.

Are compounded GLP-1 medications safe?

Compounded medications from licensed, state-inspected pharmacies use the same active ingredient as brand-name drugs. However, they are not individually FDA-approved. The key is ensuring your provider sources from a reputable, licensed compounding pharmacy. Ask about their pharmacy's licensing and inspection history.

Does GLP-1 medication lower testosterone in men?

Short answer: no — in most cases it does the opposite. Research shows significant weight loss can normalize testosterone levels in men with obesity-related low-T. Muscle loss during rapid weight loss is a real concern; that's a training and protein intake problem, not a hormone problem.

What's the cheapest option?

For compounded GLP-1, Embody starts at $149/month and Gala offers a flat $179/month regardless of dose. For brand-name medications, Sesame Care offers transparent pricing with potential insurance integration. Prices change frequently — click through to each provider for current rates.

Does MenRxFast earn commissions?

Yes. We earn a referral commission when you sign up through links on our site. This doesn't change the price you pay. We only list licensed providers, and our comparisons are based on publicly available information.

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